natural alternatives to isosorbide mononitrate

This is called tolerance, and it cannot be fixed by raising the dose of the medication. Store at room temperature away from light and moisture. Drug information provided by: IBM Micromedex. It does not have such side effects. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? WebMD does not provide medical advice, diagnosis or treatment. In the US - Call your doctor for medical advice about side effects. 1996 Dec;3(12):802-806. doi: 10.1097/00045391-199612000-00003. ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. This is not a complete list of possible side effects. Isosorbide mononitrate (Monoket) can cause some serious health issues. This is called a medicine interaction. Unless your doctor tells you otherwise, continue your normal diet. Talk to your doctor if you are using marijuana (cannabis). Tolerance is more likely to happen if you don't take your dose at the same time every day. Copyright 2023 IBM Watson Health. Herbal medications in cardiovascular medicine. Of the total drug interactions, Accessed Sept. 7, 2022. All rights reserved. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). These side effects may go away during treatment as your body adjusts to the medicine. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Herbal supplements are natural, so they must be safe, right? Then, there was a two-week placebo washout, after which the alternative treatment was given. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. Otherwise, call a poison control center right away. Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. Nitrates in the management of acute coronary syndrome. Isosorbide mononitrate systemic 60 mg (A ID). Talk to your provider if you notice your chest pain starts to get worse. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Discuss the risks and benefits with your doctor. (2) One in 3 patients never experienced headache from the given dosages. If you notice any other effects, check with your healthcare professional. A total of 195 drugs are known to interact with isosorbide mononitrate: A total of 330 drugs are known to interact with aspirin: A total of 239 drugs are known to interact with nitroglycerin: No known alcohol/food interactions. These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. This risk may be even higher for certain groups. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. Liperoti R, et al. The effects of this exposure on a nursing infant are unknown. This list covers only some interactions. In: Current Medical Diagnosis & Treatment 2022. Sildenafil ( Viagra ), tadalafil ( Cialis ), avanafil ( Stendra ),and vardenafil ( Levitra) increase the blood pressure lowering effects of isosorbide mononitrate and may cause excessive reductions in blood pressure. If you miss a dose, take it as soon as you remember. All Rights Reserved. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). These headaches may be a sign that the medication is working as it should. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. These relax smooth muscle within the blood vessels, widening them and making it easier for blood and oxygen to reach the heart Calcium antagonists (eg, diltiazem, nifedipine, nimodipine, verapamil). Do not store in the bathroom. Isosorbide mononitrate helps to prevent angina chest pain from developing. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. DUMQOL (DUtch Mononitrate Quality of Life) Study Group. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. It works and leaves the body quickly, so it needs to be taken twice a day. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Eur Heart J. Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma Your doctor will schedule your doses so that there is a period of time every day when you are not exposed to isosorbide. Take extra precautions to avoid falling during your treatment with isosorbide. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. Do not keep out-of-date or unwanted medicines. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Along with its needed effects, a medicine may cause some unwanted effects. St. Joseph 81 mg Aspirin Enteric Safety-Coated. However, you should not flush this medication down the toilet. Real test is coronary angiography. Take them to your local pharmacy which will dispose of them for you. Generic alternatives may be available. include protected health information. View more, Nitroglycerin dilates veins, relieving chest pain and lowering blood pressure. If concomitant therapy cannot be avoided, monitor clinical effects of the . It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction. My EKG showed Assess your symptoms online with our free symptom checker. Unless there is a specific reason you need the brand, the generic medication will be a better value. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Results: Usually avoid combinations; use it only under special circumstances. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. Accessed Sept. 7, 2022. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. This is a condition where the heart does not beat as efficiently as it should. . Use this medication regularly to get the most benefit from it. Keep all medicines out of the reach and sight of children. Alternative drugs to the conditions Isosorbide mononitrate treats: Angina High blood pressure Stable angina Chest pain Heart disease Heart attack Angina unstable Heart disease congenital Coronary heart disease Heart failure Pulse Heart rate irregular Coronary artery spasm Angioplasty If you become pregnant while taking isosorbide, call your doctor. Patient is a UK registered trade mark. You may report side effects to Health Canada at 1-866-234-2345. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. Aspirin has an average rating of Contact your doctor immediately if you experience any of the following: The following side effects may get better over time as your body gets used to the medication. The dose is according to the body weight and severity of the condition. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. Limit alcoholic beverages. In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). You can take your doses either before or after meals. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Medicines containing Isosorbide Mononitrate. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Registered in England and Wales. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. This medication may interfere with certain laboratory tests (including cholesterol levels), possibly causing false test results. Who should not take Isosorbide Mononitrate? Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Try our Symptom Checker Got any other symptoms? HHS Vulnerability Disclosure, Help Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). . Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. View more. Using this medicine with any of the following medicines is not recommended. Using this medicine with any of the following medicines is not recommended. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. This medicine is available only with your doctor's . An official website of the United States government. Natural Medicines. If we combine this information with your protected The https:// ensures that you are connecting to the Does Alcohol Raise Your Blood Pressure? Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. What conditions does Isosorbide Mononitrate treat? What happens if I stop taking isosorbide mononitrate (Monoket)? If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. It is components of vit. Isosorbide mononitrate helps to prevent angina chest pain from developing. Licorice. GoodRx works to make its website accessible to all, including those with disabilities. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Glyceryl trinitrate (GTN) is commonly prescribed for this. Zhonghua Yi Xue Za Zhi (Taipei). Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Saw palmetto. AHFS Patient Medication Information. Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. St. John's wort. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). It has a very short duration of action and may not be suitable for some people. It is in the nitrate class of drugs. MeSH You may report side effects to the FDA at 1-800-FDA-1088. Clipboard, Search History, and several other advanced features are temporarily unavailable. The tablet usually is taken two or three times daily. Hawthorn. 2023 Lybrate, Inc. All rights reserved. Please upgrade your browser or download modern browsers from here! Your doctor will probably tell you not to take isosorbide if you are taking one of these medications. tell your doctor if you may be dehydrated, if you have recently had a heart attack, or if you have or have ever had heart failure, low blood pressure, or hypertrophic cardiomyopathy (thickening of the heart muscles). Store it at room temperature and away from excess heat and moisture (not in the bathroom). Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. Talk to your pharmacist for more details. 72% of reviewers reported a positive effect, while 12% reported a negative effect. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. Some conditions may become worse when the drug is suddenly stopped. Lyrica and Metoclopramide drug interaction, Calcitriol and Metoclopramide drug interaction. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. This medication belongs to a class of drugs known as. Isosorbide mononitrate is very similar to isosorbide dinitrate. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks (chest pain). Mehta D. Botanical medicines. Meinertz T, Lehmacher W; Trapidil/ISDN Study Group. The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. The most common side-effect is headache. Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Don't drink alcohol while taking isosorbide mononitrate (Monoket). amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. Your doctor may tell you to take a pain reliever to treat your headaches. This medication belongs to a class of drugs known as nitrates. To help you remember, take it at the same times each day. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. Duplication for commercial use must be authorized by ASHP. Saper RB. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Natural Medicines. We study 23,548 Isosorbide mononitrate users. For details see our conditions. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (in Cafergot, in Migergot), methylergonovine (Methergine), methysergide (Sansert; no longer available in the U.S.), and pergolide (Permax; no longer available in the U.S.); medications for high blood pressure, heart failure, or an irregular heartbeat. Store in a cool, dry place, away from direct heat and light. The short-acting tablet is usually taken as 10 mg to 40 mg by mouth 2 or 3 times daily with at least a 14 hour period of time per day where you don't take any doses. AskMayoExpert. What should I know about storage and disposal of this medication? Prescription and OTC Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. Dated October 2016. Enter other medications to view a detailed report. Do not share this medication with others. from the best health experts in the business. In: Current Medical Diagnosis & Treatment 2022. Browse Drugs and Medicines. To use the sharing features on this page, please enable JavaScript. Aspirin relieves pain and inflammation and helps to thin the blood. About one-half of adults in the United States say they have used one or more supplements in the past 30 days. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Consult your doctor for more details. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. For haemoglobin formation vit. Call your doctor if you have any unusual problems while you are taking this medication. flushing - try to cut down on coffee, tea and alcohol because they can make flushing worse. Even if the medication is working, you may experience some unwanted side effects. This should pass after a few days. If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice. Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. This information is aggregated and used to produce personalized reports that patients can reference. Some of these medicine interactions can be risky. Isosorbide mononitrate works in two ways. eCollection 2021. In: Textbook of Natural Medicine. Read our editorial policy. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Nitroglycerin has an average rating of If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. Call your doctor for medical advice about side effects. And as many as 25% of people also take medicines ordered for them by their health care providers, also called prescription medicines. What should I know regarding pregnancy, nursing and administering Isosorbide Mononitrate to children or the elderly? What are the side effects of Isosorbide Mononitrate ? This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. Evening primrose. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Natural Medicines. It is also important information to carry with you in case of emergencies. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. Thirty percent of the patients never experienced headache from the given dosages. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. View all You can start a phase IV clinical trial to monitor Isosorbide mononitrate safety and effectiveness. Do not double the dose to catch up. URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. Do not take a double dose to make up for a missed one. Which drugs or supplements interact with isosorbide mononitrate? The narrowing makes it more difficult for blood to flow to your heart muscle. Change positions slowly until your body is used to the medication. prevention of anginal chest pain associated with coronary artery disease, prevent bleeding varicose vein in the esophagus. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. http://www.upandaway.org. The site is secure. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. Please note that only the generic name of each medication is listed below. Drug interactions may change how your medications work or increase your risk for serious side effects. Commonly reported side effects include: See also: isosorbide mononitrate side effects in more detail. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. B complex. Normal ecg doesn't rule out heart disease. 19 are major, 174 are moderate, and 2 are minor. Accessed Sept. 7, 2022. See also: aspirin side effects in more detail.

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